Process for synthesizing l-.gamma.-methylene glutamic acid...

Details Process for synthesizing l-.gamma.-methylene glutamic acid... Process for synthesizing l-.gamma.-methylene glutamic acid...

C - Chemistry, Metallurgy

07

C

C07C 227/22 (2006.01) C07C 229/24 (2006.01)

Patent

CA 2503029

A process for synthesizing substantially enantiomerically pure L-amino acids, particularly L- -methylene glutamic acid, and esters and salts thereof. The process includes the derivatization of (2S)-pyroglutamic acid, and the decyclization of the resulting derivative to form the desired end product.

L'invention concerne un procédé pour synthétiser sensiblement des aminoacides-L pures de manière énantiomère, en particulier un acide glutamique de L-Y-méthylène, ainsi que leurs esters et leurs sels. Ledit procédé comprend la dérivatisation de l'acide (2S)-pyroglutamique, et la décyclisation du dérivé résultant, de façon à former le produit fini souhaité.

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