Process for synthesizing phosphodiesters

C - Chemistry – Metallurgy – 07 – F

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C07F 9/09 (2006.01) C07F 9/117 (2006.01)

Patent

CA 2285417

An improved process for the production of phosphodiester compounds having formula (1). These compounds are particularly useful as contrast agents for diagnostic imaging. The process avoids the need for multiple isolation and purification steps otherwise reduced due to the formation of multiple intermediates.

Cette invention concerne un procédé amélioré qui permet de produire des composés de phosphodiesters correspondant à la formule (1). Ces composés sont particulièrement utiles en qualité d'agents de contraste en imagerie diagnostique. Ce procédé permet d'éviter le recours à de multiples étapes d'isolation et de purification dont l'effet est autrement réduit suite à la formation de multiples produits intermédiaires.

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