Process for synthesizing substituted 2-benzo[b] thiophene...

C - Chemistry – Metallurgy – 07 – D

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C07D 333/70 (2006.01)

Patent

CA 2324263

A process for the preparation of a substituted 2-benzo [b] thiophenecarboxylic acid compound or an alkali metal salt thereof, which comprises reacting a halobenzoyl derivative with mercaptoacetic acid in the presence of an alkali metal hydroxide and water. Substituted 2-benzo [b] thiophenecarboxylic acid compounds and alkali metal salts thereof are useful as intermediates for pharmaceuticals, agricultural chemicals, material preservatives, and the like.

L'invention concerne un procédé de préparation d'un composé d'acide 2-benzo[b]thiophènecarboxylique substitué ou d'un sel de métal alcalin de ce composé, le procédé consistant à mettre en réaction un dérivé d'halobenzoyle avec un acide mercaptoacétique en présence d'un hydroxyde de métal alcalin et d'eau. Les composés d'acide 2-benzo[b]thiophènecarboxylique substitués et leurs sels de métal alcalin s'utilisent comme intermédiaires dans des produits pharmaceutiques, des produits chimiques pour l'agriculture, des agents de conservation de matières, et analogues.

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