Process for synthesizing vinblastine and leurosidine

Details Process for synthesizing vinblastine and leurosidine Process for synthesizing vinblastine and leurosidine

C - Chemistry, Metallurgy

07

D

260/236.3

C07D 519/04 (2006.01)

Patent

CA 1130282

Nouveau procédé de synthèse de la vinblastine et de la leurosidine. Invention de : Pierre POTIER Pierre MANGENEY Nicole LANGLOIS Yves LANGLOIS Etablissement public dit : AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) ABREGE DESCRIPTIF La présente invention concerne un nouveau procédé de synthèse de la vinblastine et de la leurosidine. On prépare la vinblastine ou la leurosidine par hydroxylation et réduction de la .DELTA.20' déshydroxy-20' vincaleucoblastine. Les produits obtenus sont des antitumoraux connus.

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