C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
C07J 1/00 (2006.01)
Patent
CA 2147374
The invention concerns a method of alkylating estrone derivatives, the method being characterized in that a suspension of an estrone derivative in dimethylformamide is prepared, carbonic acid diester and guanidine and/or an alkylguanidine dissolved in the suspension and the substantially oxygen-free mixture allowed to react at 100-200 °C at the resulting reaction pressure.
Hubl Dieter
Seilz Carsten
Marks & Clerk
Schering Aktiengesellschaft
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