Process for the cis-selective catalytic hydrogenation of...

C - Chemistry – Metallurgy – 07 – C

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C07C 209/26 (2006.01) C07C 209/52 (2006.01)

Patent

CA 2379217

The invention relates to a process for the cis-selective preparation of cyclic amines of the sertralin type by reductive alkylation of cyclic imines or their precursors and catalytic hydrogenation in the presence of copper-containing catalysts and in the presence of a protic solvent.

L'invention concerne un procédé de préparation cis-sélective d'amines cycliques de type sertraline par alkylation réductrice d'imines cycliques ou de leurs précurseurs et par hydrogénation catalytique, en présence de catalyseurs contenant du cuivre et en présence d'un solvant protique.

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