Process for the continuous production of l-carnitine

C - Chemistry – Metallurgy – 12 – P

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195/134.7

C12P 13/00 (2006.01)

Patent

CA 1247549

ABSTRACT OF THE DISCLOSURE A process is disclosed for the continuous production of L-carnitine by a microbiological method. A microorganism of the strain DSM no. 3225 (HK 1331b) is cultivated in a bioreactor with crotonobetaine and/or .alpha.-butyrobetaine in the presence of a growth substrate. The culture fluid passes outside -the bioreactor in a circulation in which separation of the cells is carried out. A quantity of cell-free solu- tion as large as the amount fed to the bioreactor as a sub- strate, is withdrawn from the bioreactor. The L-carnitine is separated from the cell-free solution.

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