Process for the efficient production of 7-adca via...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/80 (2006.01) C12N 1/15 (2006.01) C12N 9/02 (2006.01) C12N 9/48 (2006.01) C12N 15/52 (2006.01) C12P 35/00 (2006.01) C12P 35/02 (2006.01)

Patent

CA 2168431

An overall efficient process for the preparation and recovery of 7-aminodesacetoxycephalosporanic acid (7-ADCA) via 2- (carboxyethylthio)acetyl- and 3-(carboxymethylthio)propionyl-7-ADCA, using a Penicillium chrysogenum transformant strain expressing expandase in conjunction with acyltransferase, is provided.

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