Process for the enrichment of the pregnancy-specific...

Details Process for the enrichment of the pregnancy-specific... Process for the enrichment of the pregnancy-specific...

C - Chemistry, Metallurgy

07

K

167/104, 530/15.

C07K 14/47 (2006.01) C07K 16/18 (2006.01) G01N 33/76 (2006.01)

Patent

CA 1065305

Abstract of the disclosure: Process for the enrichment of the pregnancy-specific .beta.1-gylco- protein (SP1) from blood serum, urine or placenta extracts, which comprises contracting the starting material at a pH-value of between 4 and 9 with an antibody against the pregnancy-spe- cific .beta.1-glycoprotein, said antibody being bound onto an in- soluble carrier, separating the carrier containing the SP1 in bound form from the liquid phase and in order to isolate the SP1 treating the carrier with an aqueous medium at a pH-value of from 2 to 4 or with the solution of a substance which disso- ciatos a protein molecule at a pH-value of from 4 to 9.

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