Process for the enzymatic preparation of...

C - Chemistry – Metallurgy – 12 – P

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C12P 35/02 (2006.01)

Patent

CA 2074032

CASE MU 4200 PROCESS FOR THE ENZYMATIC PREPARATION OF 7-AMINO-CEPHALOSPORANIC ACIDS. ABSTRACT 7-amino-cephalosporanic acids having the formula Image (I) are obtained by submitting compounds having the following formula to enzymatic conversion: Image (II) wherein R represents H, OH, O-CO-R", R" being an alkyl radical with from 1 to 4 carbon atoms, R1 represents a carboxylic group. The reaction is carried out in the presence of a micro-organism selected from the Pseudomonas, Bacillus, Achromobacter genera, or in the presence of the enzyme, either free or immobilized, derived therefrom.

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