Process for the enzymatic synthesis of nucleosides

Details Process for the enzymatic synthesis of nucleosides Process for the enzymatic synthesis of nucleosides

C - Chemistry, Metallurgy

12

P

195/120

C12P 19/38 (2006.01)

Patent

CA 2008806

PROCESS FOR THE ENZYMATIC SYNTHESIS OF NUCLEOSIDES ABSTRACT OF THE INVENTION A process for synthesizing nucleosides is disclosed. The process includes the reaction of an alkylated nucleoside (such as 7-methylguanosine or 7-methylinosine) with a heterocyclic base (such as adenine, 3-deazaadenine or 1,2,4-triazole-3-carboxamide) in the presence of a nucleoside-forming enzyme to form a nucleoside that includes a glycosyl component, donated by the alkylated nucleoside, bonded to the heterocyclic base. H:\TAMK\098\PA\01.FOR

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