C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 19/58 (2006.01) A01N 43/90 (2006.01) C07H 15/26 (2006.01) C07H 19/01 (2006.01) A61K 31/71 (1990.01)
Patent
CA 2074327
110/DLR58 18496 TITLE OF THE INVENTION A PROCESS FOR THE GLYCOSYLATION OF AVERMECTIN COMPOUNDS AT THE 14a-POSITION ABSTRACT OF THE DISCLOSURE Avermectin compounds are glycosylated the 14a- position by adding the avermectin compounds to the fermentation medium of Bacillus subtilis. The 14a-methyl group of the avermectin compound is glycosylated with a glycosyl moiety, specifically a glucose group. The compounds are potent anthelmintic and antiparasite agents, and compositions for such uses are also disclosed.
Arison Byron H.
Schulman Marvin D.
Young Noel M.
Arison Byron H.
Merck & Co. Inc.
Schulman Marvin D.
Swabey Ogilvy Renault
Young Noel M.
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