Process for the isomerization of 8-substituted ergoline...

Details Process for the isomerization of 8-substituted ergoline... Process for the isomerization of 8-substituted ergoline...

C - Chemistry, Metallurgy

07

D

260/206

C07D 457/04 (2006.01) C07D 457/06 (2006.01) C07D 457/12 (2006.01)

Patent

CA 1178581

100-5476 PROCESS FOR THE ISOMERIZATION OF 8-SUBSTITUTED ERGO- LINE DERIVATIVES Abstract of the Disclosure A process for the production of a pharmacologically active ergoline having an 8.alpha. side chain includes the step of protinating the ergoline enolizate obtained from an ergoline having an enolizable group in the 8.beta. position, and where necessary con- verting the resultant ergoline product into the desired ergoline.

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