C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
195/129, 260/525
C12P 13/04 (2006.01) C07C 229/22 (2006.01) C07C 233/83 (2006.01) C07D 265/08 (2006.01)
Patent
CA 1339708
The invention relates to a process for the manufacture of compounds of formula (see fig.I) in which R2 represents hydrogen or an esterifying radical and R3 represents hydrogen or the acyl radical of a carboxylic acid or of a carbonic acid semiester, or a salt thereof which process comprises reducing a compound of formula (see fig.II) in which R2 and R3 have the meanings mentioned, or a salt thereof, with baker's yeast and, if required, converting a resulting free compound into a salt or converting a resulting salt into a free compound or into a different salt. The compounds produced by the process are useful as intermediates in the production of starting materials for the manufacture of .beta.-lactam antibiotics.
616918
Ramos Gerardo
Schneider Peter
Ag Ciba-Geigy
Fetherstonhaugh & Co.
Novartis Ag
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