C - Chemistry – Metallurgy – 08 – B
Patent
C - Chemistry, Metallurgy
08
B
C08B 37/00 (2006.01) A61K 31/726 (2006.01) A61K 31/727 (2006.01) A61K 31/737 (2006.01) C07H 1/00 (2006.01) C08B 37/08 (2006.01) C08B 37/10 (2006.01)
Patent
CA 2489866
A new method is described for the oversulfation of (epi)KS-N-sulfates to obtain (epi)K5-amine-O-oversulfates at extremely high degree of sulfation and for the transformation of these intermediates into new Nacyl-(epi)K5-amine-O- oversulfates basically free of activity on the coagulation parameters and useful in the cosmetic or pharmaceutical field. Also described are pharmaceutical compositions containing, as one of their active ingredients, an (epi)K5-amine-O-oversulfate.
La présente invention concerne un nouveau procédé de sur-sulfatation d'(épi)KS-N-sulfates de façon à donner des (épi)K5-amine-O-sursulfates hautement sulfatés. Ce procédé permet en outre de transformer ces intermédiaires en de nouveaux Nacyl-(épi)K5-amine-O-sursulfates complètement neutres par rapport à la coagulation, et utilisables à des fins cosmétiques et pharmaceutiques. L'invention concerne enfin des compositions pharmaceutiques dont l'un des principes actifs est un (épi)K5-amine-O-surrsulfate.
Oreste Pasqua Anna
Zoppetti Giorgio
Glycores 2000 S.r.l.
Robic
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