Process for the manufacture of .alpha.,.beta.-unsaturated...

C - Chemistry – Metallurgy – 07 – C

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C07C 57/58 (2006.01) C07C 51/36 (2006.01) C07C 51/377 (2006.01) C07C 57/42 (2006.01) C07C 59/56 (2006.01) C07C 59/64 (2006.01) C07D 235/16 (2006.01)

Patent

CA 2195617

.alpha.,.beta.-Unsaturated acids of the formula (see fig. I) wherein R1 signifies C1-C5-alkyl and Ar signifies an aryl group which is optionally substituted by one or more halogen, phenyl, C1-C5-alkyl, C1-C5-alkoxy, perfluorinated C1-C5-alkyl or perfluorinated C1-C5-alkoxy substituents, can be obtained from new or known compounds of the formula (see fig. III) Compounds I can be converted by asymmetric hydrogenation into corresponding optically active, saturated acids.

Acides , -insaturés de formule I (voir fig. I) où R1 représente un alkyle C1-C5 et Ar est un groupe avec substitution facultative par un ou plusieurs halogènes, ou par les groupes phényle, alkyle C1-C5, alcoxy C1-C5, alkyle C1-C5 perfluoré ou alcoxy C1-C5 perfluoré; ces acides peuvent être obtenus à partir de composés nouveaux ou connus de formule (voir fig. III). Les composés I peuvent être convertis par hydrogénation asymétrique en acides saturés correspondants, optiquement actifs.

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