C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/104.1, 260/1
C07D 499/70 (2006.01) C07D 277/74 (2006.01) C07D 499/00 (2006.01) C07D 501/56 (2006.01) C07D 501/59 (2006.01)
Patent
CA 1339312
There is described a process for the manufacture of carboxylic acid amides by acylating amines with 2-benzothiazolyl thioesters of carboxylic acids, which process comprises reacting the amine in the form of an acid addition salt. This process is especially of great advantage when the amine is not particularly stable in the form of the free base, which is frequently the case especially with 7-aminocephalosporin derivatives. 7-Acylamino-cephalosporin derivatives can be manufactured in good yield and in high purity with the novel process.
528679
Furlenmeier Andre
Weiss Urs
F. Hoffmann-La Roche & Co. Aktiengesellschaft
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
LandOfFree
Process for the manufacture of carboxylic acid amides does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Process for the manufacture of carboxylic acid amides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the manufacture of carboxylic acid amides will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1181757