Process for the manufacture of cycloalkyl and haloalkyl o-...

Details Process for the manufacture of cycloalkyl and haloalkyl o-... Process for the manufacture of cycloalkyl and haloalkyl o-...

C - Chemistry, Metallurgy

07

C

C07C 225/22 (2006.01) C07C 209/68 (2006.01) C07C 221/00 (2006.01)

Patent

CA 2136795

There is provided an improved method for the production of o-aminophenyl ketones of formula I wherein R is C3-C6cycloalkyl or C1-C6haloalkyl. Image There is also provided an effective method for the preparation of the formula I compound o-aminophenyl cyclopropyl ketone via the dehydrohalogenation of 1-(o- aminophenyl)-4-halo-1-butanone in the presence of a base and a phase transfer catalyst. Compounds of formula I are key intermediates in the manufacture of sulfamoyl urea herbicides.

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