Process for the manufacture of fluorinated benzyltriazoles

Details Process for the manufacture of fluorinated benzyltriazoles Process for the manufacture of fluorinated benzyltriazoles

C - Chemistry, Metallurgy

07

D

167/236, 260/313

C07D 249/04 (2006.01) A61K 31/41 (2006.01) C07C 33/46 (2006.01)

Patent

CA 1272201

21489-6930 Fluorinated Benzyltriazoles ABSTRACT OF THE DISCLOSURE The invention relates to novel fluorinated 1-(.alpha.- phenylalkyl)-1H-1,2,3-triazoles of formula Image (I) wherein Ph is an o-fluorinated phenyl radical which may be additionally substituted by at least one further halogen atom, alk is loweralkylidene, R1 is hydrogen, lower alkyl or a carbamoyl group which is unsubstituted or substituted by lower alkanoyl or lower alkyl, and R2 is a carbamoyl group which is unsubstituted or substituted by lower alkanoyl or lower alkyl, which have anticonvulsive properties and are useful medicaments. They are prepared by methods which are known per se.

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