Process for the manufacture of highly crystalline sodium...

Details Process for the manufacture of highly crystalline sodium... Process for the manufacture of highly crystalline sodium...

C - Chemistry, Metallurgy

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C07D 501/36 (2006.01) A61K 31/545 (2006.01) C07D 205/08 (2006.01) C07D 501/00 (2006.01) C07D 501/12 (2006.01) C07D 501/24 (2006.01) C07D 501/46 (2006.01) C07D 501/56 (2006.01)

Patent

CA 1190220

ABSTRACT OF THE DISCLOSURE A process for the preparation of sodium cefoperazone comprising the controlled addition of acetone to a water/acetone/ sodium cefoperazone solution and subsequent separating and drying the resulting crystalline sodium cefoperazone, the novel process providing a highly crystalline, stable product which is essentially free of residual organic solvents.

446699

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