Process for the manufacture of intermediates suitable to...

Details Process for the manufacture of intermediates suitable to... Process for the manufacture of intermediates suitable to...

C - Chemistry, Metallurgy

07

D

C07D 405/14 (2006.01) C07D 307/24 (2006.01) C07D 307/68 (2006.01) C07D 319/20 (2006.01) C07D 405/06 (2006.01) C07D 413/06 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2173408

1. A process is provided for the manufacture of: Image where R is: Image (Intermediate for Doxazosin) Image (Intermediate for Terazosin) Image (Intermediate for Prazosin) Image (Intermediate for Tiodazosin) comprising reacting: Image with Image I wherein R1 may be selected from H, Methyl, Ethyl and suitable lower alkyl groups, Cn H2n+1 (where n is from 3 to 5) or any other suitable group and thereafter if desired converting the resultant product to a salt thereof.

1. Un procédé est offert pour la fabrication de : Image où R est : Image (Intermédiaire pour la doxazosine) Image (Intermédiaire pour la térazosine) Image (Intermédiaire pour la prazosine) Image (Intermédiaire pour la tiodazosine) comprenant la réaction de : Image avec Image I où R1 peut être choisi parmi H, les groupes méthyle, éthyle et alkyle inférieur appropriés, Cn H2n+1 (où n est un nombre de 3 à 5) ou tout autre groupe approprié et, au besoin, la conversion du produit résultant en un de ses sels.

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