Process for the manufacture of novel topically administrable...

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A61K 45/08 (2006.01) A61K 9/10 (2006.01) A61K 31/215 (2006.01) A61K 47/00 (2006.01)

Patent

CA 1228812

Novel topically administrable pharmaceutical compositions Abstract Novel topically administrable pharmaceutical composition containing, as active ingredient, from approximately 0.1 to approximately 10 % by weight of a non-steroidal, anti-inflammatorially active compound having at least one acidic group, from approximately 10 to approximately 50 % by weight of a water-soluble, volatile lower alkanol having from 2 up to and including 4 carbon atoms, from approximately 3 to approximately 15 % by weight of an optionally self- emulsifying lipid or a mixture of lipids from approximately 0.5 to approximately 2 % by weight of a gel structure former, from approximately 1 to approximately 20 % by weight of a co-solvent, from approximately 40 to approximately 80 % by weight of water, optionally from approximately 0.5 to approximately 5 % by weight of an emulsifier if the lipid phase is not self-emulsifying and, if desired, non-essential constituents.

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