Process for the manufacture of oxetanones

Details Process for the manufacture of oxetanones Process for the manufacture of oxetanones

C - Chemistry, Metallurgy

07

D

260/368.5

C07D 305/12 (2006.01) C07D 309/12 (2006.01) C07D 309/30 (2006.01) C07F 7/18 (2006.01)

Patent

CA 1328881

Abstract A process for the manufacture of the pancreas lipase-inhibiting oxetanone ethyl esters of the formula Image wherein X is undecyl or 2Z,5Z-undecadienyl, C6 is n-hexyl, Y is isobutyl and Z is formyl or Y is carbamoylmethyl and Z is acetyl, by esterifying corresponding oxetanoneethanols, by hydrogenating the 3-undecenyl group in corresponding oxetanone ethyl ester starting materials to the undecyl group X or by N-formylating or N-acetylating corresponding primary amines.

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