Process for the manufacture of spiro-linked...

C - Chemistry – Metallurgy – 07 – D

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260/243.26, 260/

C07D 471/20 (2006.01) C07D 498/20 (2006.01) C07D 513/20 (2006.01)

Patent

CA 1261325

ABSTRACT OF THE DISCLOSURE Novel processes are disclosed for the manufacture of spiro-linked pyrrolidine-2,5-diones of formula; Image which have potent inhibitory effect on aldose reductase and are useful for reduction and prevention of chronic diabetic complications. The processes are useful as improved and convenient methods for large scale manufacture.

541567

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