C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/243.26, 260/
C07D 471/20 (2006.01) C07D 498/20 (2006.01) C07D 513/20 (2006.01)
Patent
CA 1261325
ABSTRACT OF THE DISCLOSURE Novel processes are disclosed for the manufacture of spiro-linked pyrrolidine-2,5-diones of formula; Image which have potent inhibitory effect on aldose reductase and are useful for reduction and prevention of chronic diabetic complications. The processes are useful as improved and convenient methods for large scale manufacture.
541567
Fujimori Shizuyoshi
Kasuga Kazunori
Kinoshita Susumu
Masuzawa Kuniyoshi
Matsukubo Hiroshi
Borden Ladner Gervais Llp
Kyorin Pharmaceutical Co. Ltd.
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