C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/243.26, 260/
C07D 471/20 (2006.01) C07D 498/20 (2006.01) C07D 513/20 (2006.01)
Patent
CA 1261326
ABSTRACT OF THE DISCLOSURE Novel processes are disclosed for the manufacture of spiro-linked pyrrolidine-2,5-diones of the formula; Image which have potent inhibitory effects on aldose reductase and are useful for the reduction and prevention of chronic diabetic complications. These processes are useful as improved and convenient methods for large scale manufacture.
541568
Fujimori Shizuyoshi
Kinoshita Susumu
Masuzawa Kuniyoshi
Matsukubo Hiroshi
Okamura Kyuya
Borden Ladner Gervais Llp
Kyorin Pharmaceutical Co. Ltd.
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