Process for the methylation of nitrogenated heterocyclics

C - Chemistry – Metallurgy – 07 – D

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C07D 295/04 (2006.01) C07D 209/08 (2006.01) C07D 231/04 (2006.01) C07D 233/54 (2006.01) C07D 233/56 (2006.01) C07D 295/023 (2006.01)

Patent

CA 2434481

Procédé de monométhylation d'hétérocycles azotés La présente invention concerne un procédé de mono- méthylation d'hétérocycles azotés contenant au moins un atome d'azote lié à un atome d'hydrogène, par réaction de l'hétérocycle azoté avec du carbonate de diméthyle. La réaction est effectuée à une température comprise entre 100°C et 200°C et une pression comprise entre 0,93.10 5Pa et 1,07.10 5Pa. Le méthanol produit au cours de la réaction est distillé au fur et à mesure de sa formation.

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