Process for the monitoring of contaminant removal during the...

Details Process for the monitoring of contaminant removal during the... Process for the monitoring of contaminant removal during the...

G - Physics

01

N

G01N 33/15 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2484529

Process for the monitoring of contaminant removal during the purification process of a pharmaceutical product produced by a host cell, wherein at least two different samples taken during the purification process of the pharmaceutical product are incubated with at least one protein biochip array and in that the contaminants bound to the protein biochip array are subsequently detected. Preferably samples are taken before the first purification step and after each subsequent purification step.

Procédé pour contrôler l'élimination d'un contaminant pendant le processus de purification d'un produit pharmaceutique produit par une cellule hôte. Au moins deux échantillons différents prélevés durant le processus de purification du produit pharmaceutique sont incubés avec au moins un jeu ordonné d'échantillons de biopuces protéiques; et les contaminants liés audit jeu ordonné d'échantillons de biopuces protéiques sont subséquemment détectés. De préférence, les échantillons sont prélevés avant la première étape de purification et après chaque étape de purification subséquente.

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