Process for the optical resolution of the racemic...

Details Process for the optical resolution of the racemic... Process for the optical resolution of the racemic...

C - Chemistry, Metallurgy

07

D

C07D 237/04 (2006.01)

Patent

CA 2314115

Process for the preparation of racemic 6-(4- amino-phenyl-5-methyl-pyridazin-3(2H)one of formula Image as an intermediate for obtaining optically substantially pure (-) enantiomer of [[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl] hydrazono]propanedinitrile. The pure enantiomer is useful as a cardiotonic agent, antihypertensive and vasodilator for the treatment of congestive heart failure.

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