Process for the peparation of iodophor compounds and methods...

Details Process for the peparation of iodophor compounds and methods... Process for the peparation of iodophor compounds and methods...

A - Human Necessities

61

K

402/478, 134/5,

A61K 33/18 (2006.01) A01N 59/12 (2006.01) A61K 47/48 (2006.01)

Patent

CA 1099728

300344 ABSTRACT OF INVENTION An improved process for preparing iodophor preparations which comprises adding an ion selected from the group consisting of iodate, bromate, chlorite, chromate, hypo- chlorite, permanganate and persulfate ions and hydrogen peroxide to the iodine carrier selected from the group con- sisting of povidone, cationic, anionic and nonionic detergent compounds and an iodide salt, to result in a substantially pure iodophor compound which is virtually free of autode- graded iodide ion contamination and unreacted elemental iodine, said iodophor compounds exhibiting an enhanced stability. The process is also applicable to eliminate the presence of elemental iodine contaminants, iodide contam- ination and loss of titratable iodine during the process pre- paring pharmaceutical dosage forms containing iodophor active ingredients to enhance the stability and potency of the respective product.

300344

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