Process for the preparation of...

C - Chemistry – Metallurgy – 07 – D

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C07D 473/30 (2006.01) C07D 473/00 (2006.01)

Patent

CA 1276148

Abstract "PROCESS FOR THE PREPARATION OF .alpha. -N-[HYPOXANTHIN-9-YL)- PENTYLOXYCARBONYL]-ARGININE" The .alpha.-N-[(hypoxanthin-9-yl)-pentyloxycarbonyl]-argi- nine of formula I: (I) Image endowed with immunomodulating activity, is advantageously obtained by acylating N7-nitroarginine with (hypoxanthin- 9-yl)pentyloxycarbonylchloride, and subsequent elimination of the nitro group by means of hydrogenolysis.

547042

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