Process for the preparation of 2-¬2-¬4-¬(4-chlorophenyl)...

Details Process for the preparation of 2-¬2-¬4-¬(4-chlorophenyl)... Process for the preparation of 2-¬2-¬4-¬(4-chlorophenyl)...

C - Chemistry, Metallurgy

07

D

260/267.1

C07D 295/15 (2006.01) C07D 295/088 (2006.01)

Patent

CA 1317300

A B S T R A C T A process for the preparation of 2-[2-[4-[(4-chlorophenyl)phenylmethyl]- 1-piperazinyl]ethoxy]-acetic acid and its dihydrochloride, wherein 2-[2- [4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-acetonitrile is hydrolysed in an aqueous, alcoholic or aqueous-alcoholic medium by a base or by an acid, and, if desired, the acid thus obtained is converted into its dihydrochloride.

614709

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