Process for the preparation of 2,3-dihydroazepine compounds

Details Process for the preparation of 2,3-dihydroazepine compounds Process for the preparation of 2,3-dihydroazepine compounds

C - Chemistry, Metallurgy

07

C

C07C 229/18 (2006.01) C07C 227/14 (2006.01) C07D 223/16 (2006.01)

Patent

CA 2384145

A process for preparing 2,3-dihydroazepine compounds of general formula (1) or salts thereof inexpensively and simply, characterized by reacting a compound of general formula (2) or a salt thereof with a compound of general formula (3) or a salt thereof to form a compound of general formula (4) or a salt thereof and subjecting the obtained compound or salt to esterification and ring-closing reaction.

On décrit un procédé de préparation simple et peu coûteux de composés 2,3-dihydroazépine de formule (1) ou de leurs sels. Le procédé consiste à faire réagir un composé de formule (2) ou un sel de ce composé avec un composé de formule (3) ou un sel de ce composé pour former un composé de formule (4) ou un sel de ce composé; puis à soumettre le composé obtenu ou son sel à une estérification et à une réaction de fermeture de cycle.

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