Process for the preparation of 2-alkyl-4-acyl-6-tert-...

C - Chemistry – Metallurgy – 07 – C

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C07C 49/835 (2006.01) C07C 45/46 (2006.01) C07C 45/79 (2006.01) C07C 45/81 (2006.01)

Patent

CA 2106786

The subject invention relates to a process for the preparation of 2-alkyl-4-acyl-6-tert-butylphenol compound having chemical structure (1), wherein -R is an aliphatic group having a terminally unsaturated moiety selected from -C~CH and -CH=C=CH2, and R' is selected from saturated straight, branched or cyclic alkyl having from 1 to about 10 carbon atoms; the 2-alkyl-4-acyl-6-tert-butylphenol compound being produced in a reaction mixture comprising the corresponding 2-alkyl- 6-tert-butylphenol (2), the corresponding carboxylic acid: RCOOH, and trifluoroacetic anhydride.

L'objet de l'invention concerne un procédé pour la préparation d'un composé de 2-alkyl-4-acyl-6-tert-butylphénol de structure chimique (1), où -R est un groupe aliphatique ayant une partie insaturée en position terminale choisi parmi -C~CH et -CH=C=CH2, et R' est un alkyle saturé linéaire, ramifié ou cyclique comptant de 1 à environ 10 atomes de carbone; le composé 2-alkyl-4-acyl-6-tert-butylphénol étant produit dans un mélange réactionnel comprenant le 2-alkyl-6-tert-butylphénol correspondant (2), l'acide carboxylique correspondant : RCOOH, et de l'anhydride trifluoroacétique.

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