Process for the preparation of 2-bromo-.alpha.- ergocryptine

Details Process for the preparation of 2-bromo-.alpha.- ergocryptine Process for the preparation of 2-bromo-.alpha.- ergocryptine

C - Chemistry, Metallurgy

07

D

260/206.3

C07D 519/02 (2006.01)

Patent

CA 1256103

PROCESS FOR THE PREPARATION OF 2-BROMO-.alpha.-ERGOCRYPTINTE A b s t r a c t The invention relates to a novel process for the preparation of 2-bromo-.alpha.-ergocryptine and its acid addition salt by brominating .alpha.-ergocryptine in such a way that the bromination is carried out at room temperature by using a dimethylsulphoxide-hydrogen bromide mixture containing no more than 0.02 % of water and, if desired, converting the thus-obtained 2-bromo-.alpha.-ergocryptine to an acid addition salt in a known manner.

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