Process for the preparation of 2-chloro and...

C - Chemistry – Metallurgy – 07 – C

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C07C 209/62 (2006.01) C07C 209/74 (2006.01) C07C 211/52 (2006.01) C07C 213/00 (2006.01) C07C 227/20 (2006.01) C07C 229/56 (2006.01) C07C 231/12 (2006.01) C07C 233/15 (2006.01) C07C 233/25 (2006.01) C07C 237/30 (2006.01)

Patent

CA 2059884

2-Chloro and 2,6-dichloroanilines, optionally substituted in the 3-, 5-, and/or 6-position are prepared from the corresponding anilides by selective bromination, chlorination, reduction and hydrolysis. The selectivity of the process for introducing chlorines ortho to the amino group is very high.

Méthode de préparation de 2-chloro- et de 2,6-dichloroanilines, facultativement substituées aux positions 3-, 5- et/ou 6-, à partir des anilides correspondants, par bromation, chloration, réduction et hydrolyse sélectives. Le procédé est très sélectif en ce qui concerne la substitution de groupes chloro en position ortho par rapport au groupe amino.

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