Process for the preparation of...

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C - Chemistry, Metallurgy

07

D

C07D 405/00 (2006.01) C07D 295/112 (2006.01) C07D 295/205 (2006.01) C07D 307/85 (2006.01)

Patent

CA 2393183

1. Process for the preparation of 5-(1-piperazinyl)benzofuran-2-carboxamide in which, as intermediate step, 5-bromosalicylaldehyde or one of its derivatives is reacted in a transition metal-catalysed amination with R2-piperazine, in which R2 is as defined in Claim 1.

L'invention concerne un procédé de préparation de 5-(1-pipérazinyl)-benzofuran-2-carboxamide, l'étape intermédiaire consistant à faire réagir du 5-brome-salicylaldéhyde ou un de ses dérivés dans le cadre d'une amination catalysée par métal de transition avec de la R<2>-pipérazine, R<2> ayant la signification mentionnée dans la revendication 1.

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