Process for the preparation of...

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C - Chemistry, Metallurgy

07

C

C07C 251/48 (2006.01) C07C 59/88 (2006.01) C07C 69/738 (2006.01) C07C 69/76 (2006.01) C07C 229/34 (2006.01) C07C 229/38 (2006.01) C07C 249/08 (2006.01) C07C 251/60 (2006.01) C07D 217/00 (2006.01) C07D 295/155 (2006.01)

Patent

CA 2194203

There is described a process for the preparation of a compound of formula I Image in which process: a) a compound of formula II Image is reacted with an organolithium compound of formula III Li-R7 (III) b) the resulting lithium complex is reacted with a compound of formula IV Y1-CO-CO-Y1 IV to form a compound of formula V Image c) that compound is, in either order, c1) oximated with O-methylhydroxylamine; or oximated with hydroxylamine and then methylated or fluoromethylated or difluoromethylated; c2) reacted with a chloroformic acid ester. X, m, Y, R1 to R3 and R7 are as defined in the description.

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