Process for the preparation of...

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C - Chemistry, Metallurgy

07

D

C07D 211/44 (2006.01) C07D 211/00 (2006.01) C07D 211/16 (2006.01) C07D 213/00 (2006.01) C07D 401/04 (2006.01)

Patent

CA 2282480

A process for preparing 10,11-dihydro-5H-dibenzo[a,d]cyclohept-5-enes (e.g. loratadine) by reacting a dibenzozuberone with an aliphatic ketone in the presence of low valent titanium.

Procédé permettant de préparer des 10,11-dihydro-5H-dibenzo[a,d]cyclohept-5-ènes (par exemple, la loratadine) en faisant réagir une dibenzosubérone avec une cétone aliphatique, et ce, en présence de titane de faible valence.

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