Process for the preparation of...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 333/20 (2006.01)

Patent

CA 2493228

The present invention relates to a process for the preparation of compounds of the general formula (I) by catalytic enantioselective hydrogenation of the corresponding ketones. There are used inter alia ruthenium catalysts with chiral diamines and chiral biphosphines as ligands.

L'invention concerne un procédé de préparation de composés de formule générale (I) par l'hydrogénation énantiosélective et catalytique de cétones correspondantes. On utilise entre autres des catalyseurs au ruthénium avec des diamines chirales et des biphosphines chirales en tant que ligands.

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