Process for the preparation of...

Details Process for the preparation of... Process for the preparation of...

C - Chemistry, Metallurgy

07

J

C07J 1/00 (2006.01) C07C 33/042 (2006.01)

Patent

CA 2043280

ABSTRACT OF THE DISCLOSURE This invention relates to a process for the preparation of 10-(2-propynyl)-estr-4-ene-3,17-dione, whereby this compound is synthesized utilizing ketals prepared from the addition of 2,2-dimethyl-1,3-propanediol to the starting compound, 19-norandrost-5(10)-ene-3,17-dione (NAD). A new process for the addition of the propynyl group to steroid epoxides by means of higher order cuprates is also described herein. M01373A

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