Process for the preparation of (2r)-2-propyloctanoic acid

Details Process for the preparation of (2r)-2-propyloctanoic acid Process for the preparation of (2r)-2-propyloctanoic acid

C - Chemistry, Metallurgy

07

C

C07C 53/128 (2006.01) C07C 51/36 (2006.01) B01J 23/42 (2006.01)

Patent

CA 2364308

A process for the preparation of (2R)-2-propyloctanoic acid which is characterized by subjecting (2S)-2-(2- propynyl)octanoic acid or (2S)-2-(2-propenyl)octanoic acid to reduction using platinum on carbon. This process gives (2R)-2-propyloctanoic acid having high optical purity without isomerization.

Cette invention se rapporte à un procédé de préparation d'acide (2R)-2-propyloctanoïque, qui se caractérise par une opération consistant à soumettre de l'acide (2S)-2-(2-propynyl)octanoïque ou de l'acide (2S)-2-(2-propényl)octanoïque à une réduction avec du platine-carbone. Ce procédé permet de produire de l'acide (2R)-2-propyloctanoïque ayant une pureté optique élevée, non accompagnée d'isomérisation.

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