Process for the preparation of 3-[(4-bromo-2-...

Details Process for the preparation of 3-[(4-bromo-2-... Process for the preparation of 3-[(4-bromo-2-...

C - Chemistry, Metallurgy

07

D

260/264.3

C07D 237/32 (2006.01)

Patent

CA 1300142

0231/DLR5 17599IA TITLE OF THE INVENTION Improved Process for the Preparation of 3-[(4-Bromo-2- fluorophenyl)methyl]-3,4-dihydro-4-oxo-1-phthalazine- acetic Acid. ABSTRACT OF THE DISCLOSURE There is disclosed an improved process for the preparation of 3-[(4-bromo-2-fluorophenyl)- methyl]-3,4-dihydro-4-oxo-1-phthalazineacetic acid. The process is significantly improved over the prior art process in preparing the product in a one-step process where the prior art required three steps. The instant process directly alkylates a phthalazine ring nitrogen in the presence of the acetic acid moiety without the necessity of protecting the carboxylic acid group as was necessary in the prior art preferred process. The product is useful for treating the progressive deterioration resulting from diabetes, and is of the general formula: Image

586458

Affiliated with

Also associated with

Rating

Process for the preparation of 3-[(4-bromo-2-... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of 3-[(4-bromo-2-..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of 3-[(4-bromo-2-... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1175203