Process for the preparation of 3-substituted...

C - Chemistry – Metallurgy – 07 – D

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C07D 405/12 (2006.01) C07D 211/78 (2006.01) C07D 211/90 (2006.01)

Patent

CA 2314750

Described herein is the process for the preparation of 3-substituted 4-phenyl-piperidine derivatives of formula (I) Image in which X is selected from H and F, and R is selected from the group consisting of H, C1-C6 alkyl, C3-C6 alkenyl, and benzyl, comprising three steps starting from the monoamide of malonic acid and cinnamic aldehyde, or derivatives thereof.

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