Process for the preparation of...

C - Chemistry – Metallurgy – 07 – D

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C07D 487/04 (2006.01)

Patent

CA 2263368

An improved process for the preparation of 1,2,4-triazolo[1,5-a]pyrimidine compounds comprising the reaction involving a compound of formula (II), and a compound of formula (III), in the presence of an oxidising agent and a reducing agent, wherein a metal salt is added to form a complex with the oxidised reducing agent produced in the process, and this complex is separated from the desired product.

L'invention concerne un procédé amélioré pour la préparation de composés de 1,2,4-triazolo(1,5-a)pyrimidine. Ces composés compre nnent la réaction impliquant un composé présentant la formule (II) et un composé présentant la formule (III). En présence d'un agent oxydant et d'un agent réducteur, on ajoute un sel métallique pour former un complexe avec l'agent réducteur oxydé produit au cours de ce procédé. Enfin, le complexe ainsi obtenu est séparé du produit requis.

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