Process for the preparation of...

C - Chemistry – Metallurgy – 07 – C

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C07C 217/20 (2006.01) A61K 31/135 (2006.01) C07C 213/02 (2006.01)

Patent

CA 2314988

The present invention relates to a novel process for the synthesis of isopropyl-methyl-[2-(3-n-propoxyphenoxy)ethyl]amine. Moreover, the present invention also relates to a novel intermediate and an optional purification step in the novel process. Additionally, the present invention also relates to the manufacture of a pharmaceutical formulation containing isopropyl-methyl-[2- (3-n-propoxyphenoxy)ethyl]amine and the use of purified isopropyl-methyl-[2-(3- n-propoxyphenoxy)ethyl]amine in medicine.

La présente invention concerne un nouveau procédé de synthèse d'isopropylméthyl-[2-(3-n-propoxyphénoxy)éthyl]amine. En outre, la présente invention concerne un nouvel intermédiaire et une étape de purification facultative faisant partie du nouveau procédé. La présente invention concerne également la production d'une composition pharmaceutique contenant de l'isopropylméthyl-[2-(3-n-propoxyphénoxy)éthyl]amine et l'utilisation d'isopropylméthyl-[2-(3-n-propoxyphénoxy)éthyl]amine purifiée en médecine.

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