C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 51/08 (2006.01) C07C 57/30 (2006.01)
Patent
CA 2345068
Process for the preparation of .alpha.,.alpha.-dimethylphenylacetic acid from .alpha.,.alpha.-dimethylbenzyl cyanide under normal pressure A process for obtaining .alpha.,.alpha.-dimethylphenylacetic acid wherein .alpha.,.alpha.-dimethylbenzyl cyanide is reacted in the presence of sodium hydroxide, water and a C4- and/or C5-alcohol at temperatures above 100°C and the .alpha.,.alpha.-dimethylphenylacetic acid is obtained by acidification is described.
L'invention concerne un procédé permettant de produire de l'acide alpha , alpha -Diméthylphénylacétique, selon lequel on fait réagir du alpha , alpha -Diméthylbenzylcyanure en présence de d'hydroxyde de sodium, d'eau et/ou d'un alcool C4- et/ou C5 à des températures supérieures à 100 DEG C. L'acide alpha , alpha -Diméthylphénylacétique est obtenu par acidification.
Flemming Hans-Wolfram
Korb Gerhard
Lehnert Rudolf
Rybczynski Wolfgang
Aventis Pharma Deutschland Gmbh
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sanofi-Aventis Deutschland Gmbh
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