Process for the preparation of 6-halo-pregnanes

C - Chemistry – Metallurgy – 07 – J

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C07J 5/00 (2006.01) C07J 7/00 (2006.01) C07J 71/00 (2006.01)

Patent

CA 1159049

ABSTRACT OF THE DISCLOSURE : The invention relates to a new process for the preparation of 6.alpha.-halo-3-keto-.DELTA.1,4-pregnadiene-derivatives in two-steps-synthesis affording directly 6a-halo-derivatives by reacting 3-keto-9.beta., 11.beta.-oxido-.DELTA.1,4-pregnadiene-derivatives with a suitable acylating or etherifying agent to give the corres- ponding new 3-enol-derivatives which are finally halogenated by using a suitable halogenating agent.

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