Process for the preparation of 6-substituted-imidazo [2,1-b]...

Details Process for the preparation of 6-substituted-imidazo [2,1-b]... Process for the preparation of 6-substituted-imidazo [2,1-b]...

C - Chemistry, Metallurgy

07

D

C07D 513/04 (2006.01)

Patent

CA 2703300

The present invention is related to the a new process for the preparation of 6-substituted-imidazo [2,1 -b] thiazole-5-sulfonyl halides of formula (I), comprising gradually adding a compound of formula (II), into a heated solution of R1SO3H where R1 represents F or Cl, and R2 represents H, F, Cl, Br, S, (C1C6)alkyl, (C1-C6)alkoky or triftuoromethyl.

La présente invention porte sur un nouveau procédé pour la préparation d'halogénures substitués en 6 d'imidazo-[2,1-b]-thiazole-5-sulfonyle de formule (I), consistant à ajouter progressivement un composé de formule (II), dans une solution chauffée de R1SO3H où R1 désigne F ou Cl et R2 désigneH, F, Cl, Br, S, alkyle en C1-C6, alcoxy en C1-C6 ou trifluorométhyle.

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