Process for the preparation of 7.alpha.-alkoxy-3-cephem...

C - Chemistry – Metallurgy – 07 – D

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C07D 501/04 (2006.01) A61K 31/545 (2006.01) C07D 501/16 (2006.01) C07D 501/18 (2006.01) C07D 501/57 (2006.01) C07D 501/60 (2006.01) C07D 519/00 (2006.01)

Patent

CA 1049500

ABSTRACT 2-(7.alpha.-Alkoxy-7.beta.-benzylideneamino-3-cephem-4- carbonyl)-s-triazolo [4,3-a) pyrid-3-one derivatives are prepared by reacting the corresponding 2-(7- benzylideneamino-3-cephem-4-carbonyl)-s-triazolo [4,3-a) pyrid-3-ones with a benzoquinone having an electron-attracting substituent, and reacting the product with a lower alkanol. The compounds produced are useful as intermediates in the synthesis of cephalosporin antibiotics.

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