Process for the preparation of a benzamide derivative

C - Chemistry – Metallurgy – 07 – C

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260/550.8

C07C 233/00 (2006.01)

Patent

CA 1239938

ABSTRACT OF THE DISCLOSURE The invention provides a process for the preparation of 2-hydroxy-5-[1-hydroxy-2-[1-methyl-3-phenylpropyl))amino]ethyl} benzamlde of the formula ( I ) Image and pharmaceutlcally acceptable acld addltion salts thereof which comprises hydrogenating 2-hydroxy-5-{1-hydroxy-2-[(1-phenyl-but- 1-ene-3-ylldene)lmlno]ethyl}benzamlde of the formula (V) Image and, if desired, converting the compound of the formula I thus obtained into a pharmaceutically acceptable acid addition salt. The present invention also provides a compound of the formula V .

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